Biological Sciences (PhD)

An Investigation into Stereopsis and the Significance of Crossed vs Uncrossed Disparity Evolutionary Biology of Transposable Elements in Unicellular Eukaryotes Evolutionary Cell Biology of Metabolism in Unicellular Eukaryotes Genomic investigations of unique environmental bacteria. Glycosylation as a regulator of development, metabolic physiology and disease Identification of the molecular mechanisms of longevity in long-lived mutants of insulin and Klotho signalling Investigation of the evolution and polymorphic variation of molybdoflavoenzymes Investigation of the evolution and polymorphic variation of vitamin K epoxide reductases Isolation and characterisation of novel alkaliphilic microorganisms Mechanisms of cell death in carcinoma cells and their exploitation as novel cancer therapy targets Microbial Studies of Radioactive Waste Disposal Molecular Evolution Of The Unicellular Relatives of Animals Museomics approaches to uncover long-term temporal changes in genetic diversity and population structure of yellow-necked mice (Apodemus flavicollis) Pathways for cell adhesion and their role in skin integrity Protein replacement for the treatment of congenital ichthyosis Role of p63 in epidermal differentiation Structural Studies of Borrelia Outer Membrane Proteins The importance of cannabinoids for epidermal cells The role for ceramide synthase 3 in epidermal differentiation The role of DNA polymerases in aging of the mitochondrial genome The role of microbial biofilms in the modulation of intestinal epithelial function The role of outer membrane vesicles in the pathogenesis of Gram negative bacteria The role of polyphosphates in mammalian cells Topical protein delivery for the treatment of genetic skin diseases Understanding the mechanisms of carcinogenesis in epithelial cells using physiologically-relevant in vitro models. Use of physiologically-relevant in vitro skin models for the design of medical devices to target pathological skin-related conditions and disease.